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相关概念视频

Formation of Muscle Fibers from Myoblasts01:13

Formation of Muscle Fibers from Myoblasts

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De novo myogenesis, or the formation of muscle fibers, begins during the early embryonic stages. The skeletal muscle is formed from somites– blocks of embryonic cell layers. The somites are further divided into dermatomes, myotomes, sclerotomes, and syndetomes. Among these, the myotomes give rise to muscle fibers.
Muscle progenitor cells (MPCs) are formed from the myotomes. MPCs express genes that encode the transcription factors Pax3 and Pax7. Along with Pax 3/7, other transcription...
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Transgenic Organisms

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Overview
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Ribosome Profiling02:24

Ribosome Profiling

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Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
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Cell Specific Gene Expression01:58

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相关实验视频

Updated: Sep 19, 2025

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform
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转录学数据用于山羊的肌肉发育.

Yu Pei1,2, Rongsheng Xi1,2, Wenmeng Jiang1,2

  • 1College of Animal Science and Technology, Hunan Agricultural University, Changsha, 410128, China.

Scientific data
|June 2, 2025
PubMed
概括
此摘要是机器生成的。

这项研究绘制了关键肌肉中的山羊转录组图,识别了基因表达和调节元素. 这些发现提供了关于肌肉发育和通过精密育种改善肉质的见解.

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Preparation of Primary Myogenic Precursor Cell/Myoblast Cultures from Basal Vertebrate Lineages
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Author Spotlight: Improving Beef Cattle Nutrition and Production with a Focus on Feed Efficiency and Meat Quality Traits Through Advanced Biochemical and Molecular Assays
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科学领域:

  • 牲畜基因组学 动物基因组学
  • 文字转录学 (Transcriptomics) 是一个学科.
  • 动物科学动物科学

背景情况:

  • 羊肉是全球重要的粮食来源,肌肉质量影响营养和消化能力.
  • 长极背肌和双腿肌是肉质和山羊运动的关键决定因素.

研究的目的:

  • 研究山羊肌肉发育中的基因表达模式和调控机制.
  • 为了生成一个全面的全长山羊转录组数据集.

主要方法:

  • 从怀孕的山羊和胎儿身上收集了长腰肌和双腿肌肌肉.
  • 使用牛津纳米孔技术 (ONT) 进行了全长的转录组测序.
  • 分析序列数据以识别转录,替代拼接事件和长非编码RNA (lncRNAs).

主要成果:

  • 产生了超过1.69亿个有效的读数,将1.27亿与参考基因组对齐.
  • 确定了58,092个全长的成绩单,其中有50,338个注释.
  • 发现了89,468个替代拼接事件,并预测了5,538个lncRNAs.

结论:

  • 这项研究显著扩大了山羊转录组数据库.
  • 提供了解山羊肌肉发育,表观遗传调节和肉质的关键数据.
  • 促进精确的繁殖策略,以实现可持续的肉山羊生产.