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Updated: Sep 19, 2025

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干扰素调节因子8诱导成熟中性粒细胞的内在功能变化

Laura Polmann1,2, Janna Carina Grimm1, Johannes Roth1

  • 1Insitute of Immunology, University of Muenster, Roentgenstraße 21, Muenster 48149, Germany.

Journal of leukocyte biology
|June 3, 2025
PubMed
概括

干扰素调节因子8 (IRF8) 缺乏会损害中性粒细胞对炎症的反应,减少细胞因子的产生和病原体的消除. 然而,中性粒细胞外细胞陷形成 (NETosis) 仍然不受影响,突出显示了IRF8在中性粒细胞效应因子功能的特定作用.

关键词:
在 IRF8 中,我们可以使用 IRF8.功能性质的功能性质.主要和ER-HoxB8中性粒细胞.

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