深度学习模型对目标听觉脑干响应检测的比较:一个多中心验证研究
Yin Liu1,2, Lingjie Xiang1, Qiang Li1
1School of Communications and Information Engineering, Chongqing University of Posts and Telecommunications, Chongqing, China.
Trends in hearing
|June 3, 2025
概括
深度学习模型,特别是基于变压器的架构,如PatchTST,显示了准确的听觉脑干反应 (ABR) 检测的希望. 大量,多样化的数据集对于开发可靠的临床ABR解释系统至关重要.
科学领域:
- 听力学 听力学是指听力学.
- 人工智能的人工智能
- 生物医学信号处理
背景情况:
- 临床听觉脑干反应 (ABR) 的解释依赖于主观视觉检查,导致变化.
- 深度学习 (DL) 显示了客观ABR检测的潜力,但由于小型,非多样化的数据集,它与现实世界的临床数据扎.
研究的目的:
- 评估使用大型多中心临床数据集检测ABR的9个DL模型的概括性.
- 为了比较卷积神经网络 (CNN),基于变压器的模型和混合架构的性能,用于ABR检测.
主要方法:
- 利用来自13813名参与者的128,123个标记ABR的主要数据集进行DL模型的培训和测试.
- 在持有和外部数据集上评估了9个DL模型,包括CNN (AlexNet,VGG,ResNet) 和变压器 (变压器,PatchTST,微分变压器,微分PatchTST).
- 性能指标包括准确性和接收器操作特征曲线 (AUC) 下的区域,并对数据集大小,多样性和辅助输入特征进行了额外的分析.
主要成果:
- 在初级测试组中,ResPatchTST模型获得了最高的性能 (精度:91.90%,AUC:0.976).
- 基于变压器的模型,特别是补丁时间序列变压器 (PatchTST),在各种外部临床数据集中表现出卓越的概括性.
- 更大,更多样化的数据集和获取参数/人口特征的纳入改善了模型的稳定性和跨中心概括性.
结论:
- 基于变压器的DL模型显示出在临床实践中准确和可概括的ABR检测的巨大潜力.
- 在临床上可靠的ABR解释系统的开发需要使用大型,异构的数据集.
- DL提供了一条通往更客观和更一致的ABR分析的道路,减少从业者间的变化.
相关概念视频
01:15Auditory Pathway
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
01:17Auditory Perception
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the cochlea, a...
01:21Perceiving Loudness, Pitch, and Location
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...