睡眠障碍呼吸和神经发育与口腔裂2个月大的婴儿语音前功能之间的关联:可行性研究
Amy L Conrad1, Kathleen Wermke2, Jesse Goldstein3
1Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
概括
这项研究证明了这一点.
科学领域:
- 儿科医学 儿科医学
- 发育神经科学的发展神经科学.
- 语音语言病理学 语言病理学
背景情况:
- 患有口腔裂的婴儿可能会面临新兴语言和言语前发育方面的挑战.
- 了解口腔裂,神经发育和早期沟通之间的关系至关重要.
研究的目的:
- 评估测量口腔裂和没有口腔裂的婴儿口语前技能,氧化和神经结构的可行性.
- 探索这些措施如何与口腔裂的婴儿的功能有关.
主要方法:
- 进行了一项观察性病例/对照研究,对27名2个月龄的婴儿 (5 iCL, 8 iCLP, 14 UA) 进行了观察.
- 测量包括家长报告的语言和功能 (Bayley-4 SEABQ),语音声学分析,夜间脉冲氧计和结构性MRI.
- 在两个临床环境中收集数据.
主要成果:
- 新兴语言 (100%) 和声学 (89%) 的成功率很高.
- 对氧度测量 (63%) 和MRI (70%) 观察到适度的成功率.
- 唇裂 (ICLP) 的婴儿表现出较差的新兴语言,声乐声学,以及较低的髓强度,有更多的氧气脱.
结论:
- 在婴儿期早期可以获得言语前,氧化和神经测量.
- 唇裂 (ICLP) 的婴儿在这些早期发育区域表现出更高的风险模式.
- 在患有口腔裂的婴儿接受麻醉之前,可能存在神经差异.
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