通过药用草药恢复肠-大脑功能,通过抑制炎症途径提供神经保护:系统性审查
Fatemeh Abbaszadeh1, Sajad Fakhri2, Behrang Shiri Varnamkhasti2
1Neurobiology Research Center, Institute of Neuroscience and Cognition, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Current neuropharmacology
|June 3, 2025
概括
药用草药在神经退行性疾病中表现有前途,通过调节肠-大脑轴和减少炎症. 本综述探讨了它们在神经保护和改善治疗策略方面的潜力.
科学领域:
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
- 综合医学是一个整体的医学.
背景情况:
- 神经退行性疾病 (NDD) 正在增加,需要新的疗法,提高疗效和安全性.
- 炎症机制越来越多地被认为是NDD病原体的关键贡献者.
- 肠-大脑轴,一个双向通信通道,是NDD干预的关键目标.
研究的目的:
- 系统地审查药草在神经保护中的作用.
- 评估草药对肠-大脑轴功能和NDD抗炎机制的影响.
- 探索药用草药对NDDs的新型传递系统和临床应用.
主要方法:
- 一个系统和全面的文献审查,遵循PRISMA指南.
- 在Scopus,PubMed和ScienceDirect数据库中进行的搜索.
- 手动审查参考清单和引用以确定相关研究.
主要成果:
- 富含天然产品的药用草药,作为对抗NDD的多重向剂.
- 草药在恢复肠-大脑功能和抑制神经保护的炎症通路方面表现出潜力.
- 新的输送系统可以克服药草的药理学限制,以准肠-大脑轴.
结论:
- 药用草药通过调节肠-大脑功能来提供神经保护性益处.
- 草药干预可以针对参与NDD的炎症调解者.
- 对于NDD管理,需要对草药疗法和输送系统进行进一步的研究.
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