同时抗凝药患者的流量转移:多中心经验和文献系统综述
Joanna M Roy1, Basel Musmar1, Sravanthi Koduri1
1Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia , Pennsylvania , USA.
Operative neurosurgery (Hagerstown, Md.)
|June 3, 2025
概括
在接受口服抗凝剂 (AC) 的患者中,内动脉瘤的流量转移 (FD) 显示出较低的完全封闭率. 需要进一步的研究来确定这个患者群体的最佳抗血栓策略.
科学领域:
- 神经外科 神经外科
- 干预性神经辐射学
- 血管外科 血管外科
背景情况:
- 在流量转移 (FD) 后,双重抗血小板治疗是标准的,以预防血栓栓塞事件.
- 口服抗凝药 (AC) 增加了出血风险,这给FD手术带来了挑战.
- 在同时接受AC治疗的患者中,FD的安全性和有效性需要进一步调查.
研究的目的:
- 为了评估流量转移 (FD) 的安全性和有效性,在同时服用口服抗凝剂 (AC) 的内动脉瘤患者中.
- 评估结果,包括闭塞率,并发症和这个特定患者队列中的功能状态.
主要方法:
- 在3个机构 (2018年1月至2024年1月) 进行了19名患者 (20个动脉瘤) 的回顾性分析,这些患者在AC期间接受了FD.
- 系统性文献综述报告在AC患者中FD结果的研究.
- 评估结果:血管图学阻塞 (OKM等级),术后并发症,静脉支架狭窄症和修改的兰金尺度 (mRS).
主要成果:
- 在40%的动脉瘤中实现了完整的闭塞 (OKM D级).
- 89.4%的患者是女性,平均年龄为71%.
- 20%的患者出现了无症状的静脉静脉狭窄;84.2%的患者保持了功能独立 (mRS 0-2).
- 文献审查显示,AC患者的闭塞率从25%到71.4%,延迟破裂和重新治疗风险增加.
结论:
- 同时服用口服抗凝药的患者的流量转移与较低的完整动脉瘤消灭率有关.
- 这些发现凸显了对这种人群的最佳抗血栓治疗方案的进一步研究的需要.
- 在考虑FD治疗抗凝血患者时,仔细选择和监测患者至关重要.
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