对比增强剂对诊断间歇性肺异常在自动定量CT测量中的影响
Jaeyeon Choi1, Yura Ahn1, Youngjae Kim2,3
1Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
European radiology
|June 3, 2025
概括
对比度增强对CT扫描中的自动化间歇性肺异常 (ILA) 量化影响最小. 在对比扫描后的自动化ILA测量显示了与对比扫描前的诊断性能相似的诊断性能,这表明可以接受临床使用.
科学领域:
- 放射学 放射学是指放射学
- 肺部病理学 肺部病理学
- 医疗成像医学成像
背景情况:
- 在CT扫描中越来越多地检测到间歇性肺部异常 (ILA).
- 正在开发自动化量化工具,以客观评估ILA.
- 对比度增强对自动ILA定量化的影响尚不清楚.
研究的目的:
- 评估对比度增强对ILA自动定量CT测量的影响.
- 用自动化软件比较用于ILA检测的前后对比CT扫描的诊断性能.
主要方法:
- 对1134名患者进行逆向分析,对照前和后对照胸部CT扫描进行配对.
- 基于深度学习的自动化软件用于ILA量化.
- 扫描类型之间的测量变化,一致性和诊断性能的比较.
主要成果:
- 后对比扫描量化了稍微较大的非纤维性ILA (地面玻璃不透明,网状).
- 在前后对比扫描之间的一致性很大 (κ=0.75).
- 对于ILA检测的灵敏度和特异性在比较前和后对比扫描之间是可比的,尽管两者都与放射科医生有适度的一致意见.
结论:
- 在对比度后的CT扫描上进行自动定量对于ILA评估是可以接受的.
- 放射科医生可能需要在重新分类模两可的ILA发现时提高灵敏度.
- 对比度增强不会显著改变自动ILA定量化的诊断实用性.
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