多个皮层系统影响单个肌肉vibrissa
Aman Maharjan1, Jason M Guest1,2, Jean-Alban Rathelot3
1In Silico Brain Sciences Group, Max Planck Institute for Neurobiology of Behavior-caesar, Bonn 53175, Germany.
概括
大脑皮层通过不同的大脑区域控制胡须的运动,而不仅仅是主要的运动皮层. 体感皮质也在编排胡须延伸和抑制方面发挥着关键作用.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
背景情况:
- 大脑皮层控制复杂的运动行为.
- 对于精确控制个体的神秘振动的神经基础尚未完全理解.
研究的目的:
- 确定特定的皮层区域和神经元参与控制大鼠振动的运动.
- 为了阐明底层的神经电路 vibrissa延伸.
主要方法:
- 狂犬病病毒追踪被用来识别向C3vibrissa伸展肌肉投射的神经元.
- 逆行性超神经传输将皮质输入映射到运动神经元.
主要成果:
- 不同的皮层区域,包括主要运动皮层 (vM1) 外的额头和状区域,有助于控制振动.
- 五层金字塔神经元 (L5PNs) 的很大一部分来自体感区域,特别是桶场 (vS1).
- 在vS1中,L5PN的数量和密度与vM1中的数量和密度相美,这表明vS1在发动机输出中扮演着重要的角色.
结论:
- 桶场 (vS1) 对于处理与振动运动相关的电机输出至关重要,而不仅仅是传感输入.
- 提出了一个模型,其中vM1启动伸展,vS1介导伸展的相互抑制.
- 这种配对启动和抑制机制可能是动物运动皮层和体感皮层输出的一般特征.
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