由于复发而重复的手术并不是转换的风险因素,在为克罗恩病进行腹腔镜大肠切除的患者中
Federico Ghignone1, Giovanni Taffurelli2, Federica Greco3
1Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; General and Colorectal Surgery Unit, Ospedale Santa Maria delle Croci, Ravenna, Italy.
Surgery
|June 3, 2025
概括
对于复发性克罗恩病的腹腔镜手术,其结果与初级手术相似. 之前的手术不会增加转化风险,这表明微创方法适合所有患者.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 炎症性肠道疾病 炎症性肠病
背景情况:
- 经过大肠切除的克罗恩氏病患者面临高复发率,需要重复手术.
- 至少侵入性手术在克罗恩氏病复发中的作用仍在争论中.
- 预测转换为开放性手术,并比较复发性和初级手术的结果至关重要.
研究的目的:
- 为了确定在克罗恩病的腹腔镜大肠切除过程中转换为开放性手术的预测因素.
- 评估之前的腹腔镜手术是否会增加转化风险.
- 为了比较一次性和复发性大肠切除术之间的术后结果.
主要方法:
- 对202名患者 (2017-2023) 进行了回顾性单中心队列研究,这些患者接受了为克罗恩病进行腹腔镜大肠切除术.
- 包括初级病例和复发病例.
- 单变量和多变量分析 (LASSO) 用于确定与转换和术后结果相关的因素.
主要成果:
- 转化率为10.3%;只有美国麻醉学会 (ASA) 的得分预测了转化.
- 在初级和复发性手术组之间,没有显著的结果差异 (结口,并发症,重新手术,停留时间,再入院).
- 平均逗留时间为5.2天;严重并发症发生在3.9%的患者中.
结论:
- 之前的克罗恩病手术不会增加腹腔镜大肠切除中的转化风险.
- 在一次性和复发性手术中,术后的结果是可比的.
- 对于所有患有复发性克罗恩病的患者,应考虑微创手术.
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