微塑料生物膜可能会塑造富含抗生素耐药基因的微生物群体,以增强抗生素压力下的转化
Zhijie Zheng1, Honghong Lyu2, Lan Wang1
1MOE Key Laboratory of Pollution Processes and Environmental Criteria/Tianjin Engineering Center of Environmental Diagnosis and Contamination Remediation, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.
Journal of hazardous materials
|June 3, 2025
概括
微塑料生物膜增强了地表水中的去除,但抗生素抑制了这一过程. 生物膜还增加了微生物中转化和抗生素耐药性基因之间的联系.
科学领域:
- 环境微生物学环境微生物学
- 水质科学 水质科学
- 生物地质化学循环是什么
背景情况:
- 了解抗生素和微塑料等环境压力因素下的转化对于地表水质量至关重要.
- 微塑料生物膜中转化基因 (NTGs) 和抗生素耐药性基因 (ARGs) 之间的相互作用仍未得到充分探索.
研究的目的:
- 调查聚乙烯 (PVC) 生物膜如何影响在抗生素 (西普洛素和四环素) 压力下的转化.
- 探索暴露于PVC生物膜和抗生素的地表水微生物群落中的转化功能和ARG之间的相互作用.
主要方法:
- 对形式 (酸盐和氨) 和去除速度的分析.
- 评估基因丰富性和NTGs和ARGs之间的相关性.
- 微生物社区分析,以确定主机的关键物种,其中包含两种基因类型.
主要成果:
- 与对照组相比,PVC生物膜增强了酸盐和氨的去除.
- 齐普罗夫洛克萨显著抑制了的转化,降低了酸盐的去除率.
- 在PVC生物膜中观察到NTGs和ARGs之间存在强烈的正相关性,例如Hydrogenophaga,Rhodococcus和Ignavibacterium等特定属显示出两种高丰度.
结论:
- 聚乙烯生物膜可以通过丰富特定的微生物来促进在抗生素压力下的转化,这些微生物也携带ARG.
- 微塑料生物膜在循环和表面水生态系统中抗生素耐药性的传播中发挥着复杂的作用.
- 研究结果提供了关于微塑料和抗生素对水生环境的生态影响的见解.
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