过早生育与增加的并发症和在Hirschsprung疾病中拉透后的重新手术有关
Elio R Bitar1, Mahmoud G El Baassiri2, Charbel Chidiac2
1Division of Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
The Journal of surgical research
|June 3, 2025
概括
过早分娩增加了希尔施普朗格病手术后的并发症和重新手术. 医疗保健提供者在为这些儿科患者提供术后护理时应考虑早产.
科学领域:
- 儿科手术 儿科手术
- 新生儿医学 新生儿医学
- 胃肠病学 胃肠病学
背景情况:
- 赫施普朗格病 (Hirschsprung disease,简称HD) 是一种先天性疾病,影响肠道神经系统,需要通过拉透程序进行外科纠正.
- 过早生育是儿科手术中术后并发症增加的已知危险因素,但其对HD患者的具体影响仍在调查中.
研究的目的:
- 为了研究早产和短期外科结果之间的关联,特别是30天的术后并发症和重新手术率,在患者接受了Hirschsprung病的拉透手术.
主要方法:
- 使用国家外科质量改善计划-儿科数据库 (2016-2022) 的回顾性队列研究.
- 0-18岁的患者接受了HD的拉透手术,被归类为早产 (<37周怀孕) 或满期 (≥37周怀孕).
- 使用后勤回归模型来评估早产对并发症和重新手术率的影响.
主要成果:
- 这项研究包括2603名HD患者,其中296人 (11.4%) 出生早产.
- 在手术后30天内,早产婴儿的整体并发症率 (24.3%与16.7%) 和与初始手术相关的重复手术率 (10.5%与7.0%) 显着更高.
- 多变量分析证实早产是1岁以下儿童并发症和重新手术的独立预测因素.
结论:
- 过早分娩与术后并发症和在希尔施普朗格病的拉透手术后重新手术的风险增加显著相关.
- 这些发现强调了在手术后的治疗中考虑早产和儿科HD患者风险分层的重要性.
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