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Updated: Sep 19, 2025

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
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法医SNP基因谱推断使用不同深度的全基因组测序数据

Quan Xie1, Wenting Zhao2, Wenhai Liu3

  • 1Key Laboratory of Forensic Genetics, Beijing Engineering Research Center of Crime Scene Evidence Examination, National Engineering Laboratory for Forensic Science, Institute of Forensic Science, Beijing 100038, China; Criminal Investigation Branch, Zhuzhou Municipal Public Security Bureau, Zhuzhou, Hunan 412000, China.

Forensic science international. Genetics
|June 3, 2025
PubMed
概括

全基因组测序 (WGS) 准确地推断出基因谱和生物地理起源,使用单核酸多态 (SNP) 数据. 高级测序深度 (8x及以上) 对于法医家谱是可靠的,尽管较低的深度需要进一步优化.

关键词:
基因谱推断推断 基因谱推断亲属关系的关系一个单核酸多态性多态性.整个基因组的测序.

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