家庭用剂和度对漂白功效的影响:系统性审查和网络元分析
Renata Maria Oleniki Terra1, Michael Willian Favoreto2, Tom Morris3
1Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Uvaranas, Ponta Grossa, PR, Brazil.
Journal of dentistry
|June 3, 2025
概括
大多数家用漂白剂都表现出类似的有效性,只有极端度的微小差异. 需要进一步的研究来提高牙科专业人员的证据质量.
科学领域:
- 牙科科学 牙科科学
- 生物材料是一种生物材料.
背景情况:
- 在家用漂白剂广泛用于美学牙科治疗.
- 了解不同药物和度的比较疗效对于临床决策至关重要.
研究的目的:
- 系统地审查和比较各种家庭漂白剂和度的疗效.
- 对永久牙患者的颜色变化 (ΔE, ΔSGU) 进行网络元分析 (NMA).
主要方法:
- 在多个数据库 (PubMed,Cochrane Central等) 中进行系统搜索. 和灰色文学进行了表演.
- 包括随机临床试验 (RCT),比较家庭漂白系统.
- 用贝叶斯的NMA分析了颜色变化数据;评估了偏差风险和证据质量.
主要成果:
- 53个RCT被纳入NMA,大多数研究显示出高偏差风险.
- 大多数药物和度之间没有发现有效性的显著差异.
- 在比较极端度时,注意到了差异,例如,对于 ΔE,CP为5%与CP为35-37%.
结论:
- 大多数家用漂白剂在不同度下表现出可比的有效性,表明其临床多功能性.
- 证据质量 (QoE) 一般很低,突出了需要高质量的RCT的需要.
- 未来的研究应该专注于精心设计,低偏差的RCT,以提高研究结果的确定性.
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