临床变量不能预测心脏起器患者与双关节阻塞昏迷:一个SPRITELY替代研究
Joshua Szaszkiewicz1, Robert Sheldon2, Satish Raj1
1Libin Cardiovascular Institute, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2 N 4Z6, Canada.
概括
在患有双关节阻塞和昏迷的患者中,病史上患有 asystole, supraventricular tachycardia 或糖尿病预测复发. 这一发现有助于管理对节拍抗性昏.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 临床试验 临床试验
背景情况:
- 在SPRITELY研究中,在双块患者中,心脏起器和可植入心脏监测器组之间,对昏的复发没有发现差异.
- 在患有双筋阻塞和永久起器的患者中,昏迷复发的预测因素仍然不清楚.
研究的目的:
- 确定基线临床特征,预测双筋阻塞和永久心脏起器患者的昏迷复发.
主要方法:
- 对SPRITELY随机临床试验的回顾性分析.
- 在接受心脏起器的60名患者中评估了38个基线临床变量.
- 使用单变量和多变量统计来识别显著预测因素 (p < 0.05).
主要成果:
- 在12%的患者中 (20%) 发生了复发性昏迷.
- ангиотензин受体阻断剂 (ARB) 的使用和患有心衰竭,心上高心率 (SVT) 或糖尿病的病史是不变的预测因素.
- 在多变量分析 (p = 0.03) 中,先前患有缩,SVT或糖尿病的病史独立预测了昏迷复发的情况.
结论:
- 在老年患有昏迷和双性心脏阻塞的患者中,患有心血管缩,SVT或糖尿病的病史是昏迷复发的重要预测因素.
- 这些因素可能有助于识别患有抗节律性的患者.
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