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Updated: Sep 19, 2025

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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单分子四受体激活剂的分子设计

Tristan C Dinsmore1, Jacob E Cortigiano1, Siyuan Xiang1

  • 1Department of Chemistry, Tufts University, Medford, Massachusetts 02155, United States.

Journal of the American Chemical Society
|June 3, 2025
PubMed
概括

研究人员开发了针对四种代谢受体的新型四重激活剂,包括GLP-1R,GIPR,GcgR和Y2R. 通过克服受体类别的差异, 这一突破使单剂治疗代谢障碍成为可能.

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