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Updated: Apr 30, 2026

Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex
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Published on: June 4, 2014

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在STRADA相关的大脑中通过mTOR过活性的延迟前脑刺激和抑制神经发生

Tong Pan, Grace Lin, Xuan Li

    bioRxiv : the preprint server for biology
    |June 4, 2025
    PubMed
    概括

    通过过度激活mTOR途径,STRADA中的遗传变异会导致大脑发育障碍. 在干细胞模型中抑制这种途径挽救了发育缺陷,这表明对STRADA缺陷的潜在治疗方法.

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