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Updated: Jun 14, 2025

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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计算模型预测了Rho GTPase功能与Plexin跨膜受体GAP活性在Rap1b上,通过动态全变化

Nisha Bhattarai1, Lindsay Morrison2, Alexandre F Gomes2

  • 1Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106, USA.

bioRxiv : the preprint server for biology
|June 4, 2025
PubMed
概括

模拟了plexin-GTPase相互作用,揭示了Rac1动态比Rnd1.1更受改变. 与Rac1不同,Rnd1在没有Rap1b的情况下与Plexin-B1结合更强,从而增强对细胞信号的理解.

关键词:
在GTPases中使用.分子动力学模拟的模拟.素 (Plexins) 是一种复合素.结构生物学是结构生物学.- - 二是一种.质谱法 质谱法 质谱法 质谱法

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