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Updated: Sep 19, 2025

Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules
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由线粒体衍生的dSRNA诱导的压力颗粒促进IRF3介导的纤维化反应

Jared Travers, Emily Huang, Megan R McMullen

    bioRxiv : the preprint server for biology
    |June 4, 2025
    PubMed
    概括

    转化生长因子-β (TGFβ) 通过线粒体衍生的双链RNA和压力颗粒激活干扰素调节因子3 (IRF3),促进肝纤维化. 阻断这种途径会减少肝星细胞中的纤维化反应.

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