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Updated: Jun 16, 2025

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
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G蛋白结合雌激素受体信号传递维持了雌性小鼠中的β细胞身份

Madeline R McLaughlin, Preethi Krishnan, Wenting Wu

    bioRxiv : the preprint server for biology
    |June 4, 2025
    PubMed
    概括

    与更年期相关的雌激醇 (E2) 信号损失可能会通过GPER损害胰腺β细胞的身份. 这一发现将E2缺乏与老年妇女的2型糖尿病风险联系在一起.

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