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Updated: Jun 14, 2025

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
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Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

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性别和基丁DNA糖酶表达是NDMA诱导的突变,毒性和癌症的关键敏感性因素

Jennifer E Kay1,2, Joshua J Corrigan1, Lindsay B Volk1

  • 1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139.

bioRxiv : the preprint server for biology
|June 4, 2025
PubMed
概括

男人更容易患上NDMA诱导的肝癌和突变,而AAG缺乏和男性性是关键的危险因素. 过度表达AAG会增加毒性,可能会更严重地影响女性.

关键词:
癌症 癌症 癌症 癌症修复DNA修复DNA的修复造成的DNA损伤是DNA损伤.突变 突变 突变 突变这是一种N-二甲基胺.与性别有关的差异.

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