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Updated: Sep 19, 2025

Spatial and Temporal Analysis of Active ERK in the C. elegans Germline
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非正规EGFR信号传递对于MAPK介导的上皮细胞的顶端挤出至关重要

Paola Molina, Mikiyas Daniel, Jason Wang

    bioRxiv : the preprint server for biology
    |June 4, 2025
    PubMed
    概括

    瘤基因诱导的细胞挤出,癌症机制,意外地需要表皮生长因子受体 (EGFR) 信号. 这种非正规的途径,独立于ERK,涉及E-cadherin内部化,揭示了癌症治疗的新目标.

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