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Updated: Sep 19, 2025

Chromatin Interaction Analysis with Paired-End Tag Sequencing ChIA-PET for Mapping Chromatin Interactions and Understanding Transcription Regulation
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Published on: April 30, 2012

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集体非结构性相互作用驱动着转录因子的染色质结合

Abrar A Abidi1, Gina M Dailey1,2, Robert Tjian1,2

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, United States.

bioRxiv : the preprint server for biology
|June 4, 2025
PubMed
概括

转录因子 (TF) 使用内在失序区域 (IDR) 进行染色质结合和自我关联,而不仅仅是DNA结合域 (DBD). 这些IDR促进了广泛的合作相互作用,重新定义了活细胞中的TF特异性.

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