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Updated: Sep 19, 2025

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors

Published on: December 7, 2014

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大动脉瘤风险和体质JAK2突变:多中心,基于人群的心血管查研究的见解

Lasse M Obel1,2,3, Joachim S Skovbo1,2,3, Axel C P Diederichsen1,4

  • 1Elite Centre for Individualized Medicine in Arterial Disease (L.M.O., J.S.S., A.C.P.D., L.M.R., J.S.L.), Odense University Hospital, Denmark.

Circulation
|June 4, 2025
PubMed
概括

这种JAK2 V617F突变与上升性大动脉瘤有关,更高的变异性基因频率与风险和大小的增加有关. 这种遗传因素与下降或腹腔大动脉瘤没有显著相关.

关键词:
大动脉,胸部大动脉动脉瘤克隆性血液形成大规模选

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