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相关概念视频

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

46
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
46

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In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
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在轴流支过程中不断关闭主动脉的静脉内流量可视化研究.

Guang-Mao Liu1,2, Jian-Qiang Hao1, Sheng-Shou Hu1,2

  • 1State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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概括

在使用左心室辅助器件 (LVAD) 的患者中,持续的大动脉关闭会改变血液流动,增加血栓的风险. 这项研究可视化了心室内流,揭示了入口和大动脉附近的停滞区域.

关键词:
粒子图像速度测量 粒子图像速度计血是一个血.内流是指内流的内部流.模拟的循环循环循环循环.这是一个的 vortex.

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科学领域:

  • 心血管工程 心血管工程
  • 生物医学流体动力学
  • 医疗器械研究 医疗器械研究

背景情况:

  • 左心室辅助器件 (LVAD) 对末期心力衰竭至关重要.
  • 在LVAD支过程中不断关闭大动脉会改变心室内血液动力学.
  • 这种改变会增加腹腔内血栓形成的风险.

研究的目的:

  • 在轴流支期间不断关闭大动脉的条件下分析心室内血流模式.
  • 为了研究连续的大动脉关闭对左心室 (LV) 内血液动力学参数的影响.

主要方法:

  • 在体外流动可视化实验中,使用3D打印的左心室 (LV) 模型进行了实验.
  • 模拟了包括速度分布和旋转率在内的血液动力学参数,以模拟轴向血支 (LAP31) 期间的条件.
  • 分析的重点是LV模型中的速度,旋流和速度的标准偏差.

主要成果:

  • 在所有心脏循环阶段,与大动脉关闭时,静脉内血流从二心向血入口导向.
  • 血液流速的标准偏差在检查的横截面上保持一致.
  • 在心室壁附近,血入口旁边和大动脉下方始终观察到强烈的旋转,表明停滞的流量区域.

结论:

  • 在LVAD支持期间不断关闭大动脉导致心室内血停滞.
  • 停滞发生在左心室外流通道和血液入口附近.
  • 这些发现强调了在这些特定的血液动力学条件下,左心室内血栓形成的风险增加.