解开睡眠障碍和勃起功能障碍的交集:两个EPISONO版本的结果
Monica Levy Andersen1,2, Allan Saj Porcacchia1, Guilherme Luiz Fernandes1
1Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Andrology
|June 4, 2025
概括
勃起功能障碍 (ED) 与衰老,低丸激素,抑郁症和心理健康状况不佳有关. 虽然阻塞性睡眠呼吸暂停与ED有关,但它与ED有关.
科学领域:
- 睡眠医学 睡眠医学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 流行病学 流行病学
背景情况:
- 对睡眠障碍与勃起功能障碍 (ED) 之间的联系越来越感兴趣.
- 使用来自巴西圣保罗的流行病学睡眠研究 (EPISONO) 的数据 (2007年,2015年,2018年).
- 调查ED的发病率和患病率以及相关的风险因素.
研究的目的:
- 为了确定ED,总水平和阻塞性睡眠呼吸暂停 (OSA) 之间的关系.
- 分析纵向和横截面数据以确定ED的预测因素.
- 探索心理健康在ED中的作用.
主要方法:
- 参与者 (年龄在20-80岁的男性) 接受了多睡眠和测试.
- 管理健康问卷和世界卫生组织 (WHOQOL) 生活质量评估.
- 纵向分析包括使用概括估计方程进行发病率 (N=256) 和流行率 (N=300) 计算.
- 对2018年数据的横截面分析 (N=314) 使用二项逻辑回归和调节-调节模型.
主要成果:
- 在随访期间,ED的总体发病率为10.55%,50岁以上男性的发病率更高.
- 勃起障碍的长度预测因素包括年龄 (OR=1.09),抑郁症状 (OR=1.05) 和总丸激素低 (OR=2.69).
- 更高的心理生活质量预测ED的几率较低 (OR=0.87).
- 2018年,ED患病率为20.06%,随年龄增长而增加 (OR=1.07).
- WHOQOL的心理领域与较低的ED几率 (OR=0.65) 相关.
- 呼吸暂停-呼吸暂停指数显示了年龄和丸激素之间的显著调解,但不是直接与ED有关.
结论:
- 衰老,心理生活质量,水平和抑郁症状是ED的关键因素.
- 观察到阻塞性睡眠呼吸暂停 (OSA) 和ED之间的关联,但这取决于年龄.
- 除了衰老之外,可修改的因素,如丸激素水平,抑郁症和心理健康可以作为ED干预的目标.
关键词:
呼吸暂停 - 呼吸暂停指数流行病学流行病学这是勃起功能障碍.发生率的发生率.患病率的流行情况.心理健康 心理健康睡眠 睡眠 睡眠 睡眠 睡眠睡眠呼吸暂停 (Sleep Apnea) 是一个测试剂 测试剂 测试剂 测试剂更多相关视频
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