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Updated: Jan 18, 2026

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging
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基于生理学的药理动力学/药理动力学模型Secukinumab:剂量探索在儿童患有斑块性牛皮的患者

Liu Zhiwei1,2, Wang Wenhui1,2, Chen Tao1,2

  • 1Anhui Provincial Center for Drug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, China.

Journal of clinical pharmacology
|June 4, 2025
PubMed
概括

这项研究开发了一种药理动力学模型,以确定儿童斑块牛皮患者最佳的secukinumab剂量. 建立了基于体重的剂量建议,以确保有效的IL-17A抑制,提高治疗灵活性.

关键词:
儿科 儿科 儿科基于生理学的药理动力学 (PBPK) 模型.斑块性牛皮病是一个病.干燥的 干燥的 干燥

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