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Updated: Sep 19, 2025

Focus Formation: A Cell-based Assay to Determine the Oncogenic Potential of a Gene
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在乳腺癌中,HDAC1和REST的负调节丧失有助于MAD1过度表达

Sarah E Copeland1,2, Boya Chen1, Avtar Roopra3

  • 1Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin-Madison, Madison 53705, WI.

Molecular biology of the cell
|June 4, 2025
PubMed
概括

线索性停止缺陷1 (MAD1) 在乳腺癌中过度表达. 瘤抑制剂REST的丧失导致MAD1的增加,促进瘤生长.

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