大脑护理得分及其与心血管疾病和癌症的关联
Jasper R Senff1,2,3, Cyprien A Rivier4, Reinier Tack1,2,3
1Brain Care Labs, Department of Neurology, Massachusetts General Brigham, Somerville, 399 Revolution Drive, 02145 MA, United States.
Family practice
|June 4, 2025
概括
较高的大脑护理分数 (BCS) 与心血管疾病 (CVD) 和常见癌症风险的降低有关. 这个分数,最初是对大脑健康的,可能通过激励行为改变来促进整体健康的衰老.
科学领域:
- 老年学是一门学科.
- 预防医学 预防医学
- 公共卫生 公共卫生
背景情况:
- 大脑护理得分 (BCS) 是与患者和从业人员一起开发的,以鼓励健康行为改变,旨在减少痴呆症,中风和晚年抑郁症 (LLD) 的风险.
- 共同可修改的风险因素将大脑疾病与其他常见的与年龄有关的疾病联系起来,如心血管疾病 (CVD) 和癌症.
研究的目的:
- 调查大脑护理得分 (BCS) 与心血管疾病 (CVD) 和常见癌症类型的发病率之间的联系.
- 为了确定BCS是否对大脑健康之外的健康衰老有更广泛的影响.
主要方法:
- 使用英国生物银行 (UKB) 数据进行了Cox比例危险回归分析.
- 这项研究检查了基线BCS和事件CVD (缺血性心脏病,中风,心力衰竭) 和三种常见癌症 (肺,结直肠,乳腺) 之间的关联.
- 分析根据性别进行了调整,并按年龄分层.
主要成果:
- 总共有416,370名参与者被分析,随访时间中位数为12.5年.
- BCS增加5点与心血管疾病 (HR:0.57) 和三种常见癌症类型 (HR:0.69) 的发病率显著降低有关.
- 确定了33944例心血管疾病病例和16090例癌症病例.
结论:
- 较高的基线BCS与心血管疾病和常见癌症的发病率降低有关.
- 虽然BCS是为大脑健康而设计的,但它可能是促进整体健康衰老的宝贵工具.
- 这些发现表明,BCS可以指导个人更广泛地改善他们的长期健康结果.
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