绝经前和绝经后妇女的健康饮食模式和加速生物衰老:在不同的BMI状态之间
Wenbo Xiao1, Wen Li1, Zhanling Ruan1
1The Department of Epidemiology and Health Statistics, School of Public Health, Tianjin Medical University, Tianjin, China.
European journal of nutrition
|June 4, 2025
概括
总的来说,健康的饮食对绝经前和绝经后妇女的生物衰老没有影响. 然而,特定的食物,如海鲜蛋白质,植物蛋白质,全谷物和蔬菜,可能有助于延迟基于BMI的生物衰老.
科学领域:
- 老年学和营养科学研究
- 生殖健康和内分泌学
背景情况:
- 生物衰老是一个复杂的过程,受各种因素的影响,包括饮食.
- 绝经前和绝经后的妇女代表了生命的关键阶段,具有独特的生理变化.
- 了解饮食对这一人口群体生物衰老的影响对于健康的延长至关重要.
研究的目的:
- 通过2020年健康饮食指数 (HEI-2020) 评估的健康饮食模式与美国绝经前和绝经后妇女的生物衰老 (Phenotypic Age, PhenoAge) 之间的关联.
- 为了调查这些协会在不同的身体质量指数 (BMI) 类别.
主要方法:
- 利用了1999-2010年国家健康和营养检查调查 (NHANES) 中的4375名绝经前和绝经后妇女的数据.
- 使用9个血液生物标志物计算了饮食模式和PhenoAge的HEI-2020分数.
- 使用加权后勤回归模型,对共变量进行调整,以分析横截面关联.
主要成果:
- 总体HEI-2020得分显示,一般人群或BMI亚组中的加快衰老没有关联.
- 特定的食物成分显示出保护作用:海鲜和植物蛋白质在正常的BMI个体中 (OR:0.76,P=0.01),蔬菜和全谷物在超重个体中 (OR:0.72,P=0.004;OR:0.90,P=0.024,分别),蔬菜在肥胖个体中 (OR:0.86,P=0.051).
结论:
- 总的HEI-2020得分与绝经前和绝经后妇女的生物衰老没有相关性.
- 特定的饮食成分,包括来自海鲜和植物的蛋白质,全谷物和蔬菜,与延迟衰老有关,在BMI类别中观察到差异.
- 增加这些特定的营养丰富食物的摄入量可能有助于延迟这一群体的生物年龄.
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