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Updated: Sep 19, 2025

Time-Lapse 2D Imaging of Phagocytic Activity in M1 Macrophage-4T1 Mouse Mammary Carcinoma Cells in Co-cultures
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Time-Lapse 2D Imaging of Phagocytic Activity in M1 Macrophage-4T1 Mouse Mammary Carcinoma Cells in Co-cultures

Published on: December 14, 2019

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在多相瘤生长模型中,M1和M2巨细胞的时空空间动力学

Ioannis Lampropoulos1, Panayotis G Kevrekidis2, Christos E Zois3,4

  • 1School of Chemical Engineering, National Technical University of Athens, Iroon Polytechneiou 9, Zografou, Athens, 15780, Greece.

Bulletin of mathematical biology
|June 4, 2025
PubMed
概括

这项研究模拟了瘤微环境,以了解不同类型的巨细胞如何影响血管瘤生长. 它模拟免疫疗法,显示最初的抗瘤效果,随后复发.

关键词:
免疫治疗是一种免疫疗法.多相模型是多相模型.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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