约旦对艾滋病毒治疗的药物坚持和信仰:一个横截面分析
Sara Al-Ajlouny1, Tareq L Mukattash1, Anan S Jarab1,2
1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan.
AIDS and behavior
|June 4, 2025
概括
在约旦,许多艾滋病毒感染者 (PLHIV) 努力坚持抗逆转录病毒疗法 (ART). 对药物和较低教育水平的担忧会对遵守药物产生负面影响,这凸显了针对性干预的必要性.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 制药科学 制药科学
背景情况:
- 抗逆转录病毒疗法 (ART) 对于治疗艾滋病毒/艾滋病至关重要.
- 了解药物坚持和信念对于治疗成功至关重要.
- 约旦的艾滋病毒管理背景需要具体的调查.
研究的目的:
- 评估约旦安曼艾滋病毒感染者 (PLHIV) 之间的ART坚持率.
- 调查药物信仰与药物坚持之间的关系.
- 为了确定影响这一群体ART坚持的因素.
主要方法:
- 一项从2022年12月到2023年2月进行的横截面研究.
- 180名被诊断患有艾滋病至少六个月的PLHIV被招募.
- 使用莫里斯基药物坚持度表评估坚持,使用药物坚持问卷评估信念.
主要成果:
- 42.2%的PLHIV患者表现出低至中度的ART坚持 (坚持得分≤75%).
- 不服药的常见原因包括对药物服用时间的疏忽 (33.3%).
- 高等教育 (OR=2.10) 和感知到的药物需要 (OR=1.35) 与更好的坚持相关;增加的担忧 (OR=0.73) 与较低的坚持相关.
结论:
- 在约旦的PLHIV中,低于最佳的ART坚持是普遍存在的.
- 对药物的副作用和较低的教育程度的担忧是遵守的重大障碍.
- 建议采取解决患者担忧和加强药物教育的干预措施,以改善药物遵守和健康结果.
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