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Updated: Sep 19, 2025

Phagosome Migration and Velocity Measured in Live Primary Human Macrophages Infected with HIV-1
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巨体是HIV-1进入初级CD4+ T细胞的地点

Tomoyuki Murakami1, Ricardo de Souza Cardoso1, Praveen Manivannan1

  • 1Department of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, MI 48109.

Proceedings of the National Academy of Sciences of the United States of America
|June 4, 2025
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) 通过细胞吸收过程 - - 巨型皮诺细胞体 (macropinocytosis) 进入至关重要的CD4+T细胞. 抑制这种途径阻断了病毒的进入和感染,揭示了HIV-1细胞进入的关键机制.

关键词:
艾滋病病毒-1 艾滋病病毒-1巨型皮诺细胞瘤的发生主要的CD4+T细胞.病毒进入病毒.病毒与细胞融合是病毒与细胞的融合.

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Viral genomes exhibit remarkable diversity in size, structure, and composition, influencing their replication strategies and interactions with host cells. These genomes consist of either DNA or RNA and may be linear or circular. Additionally, they can be single-stranded or double-stranded, with each configuration affecting how the virus propagates within a host. RNA viruses, for instance, generally have smaller genomes than DNA viruses, a factor that contributes to their high mutation rates and...
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