在高血压患者的手臂动脉中通过流媒扩张 (FMD) 进行内皮功能
Elaine Alves Santos Tessier1, Carla Daltro1, Eduardo Martins Netto1
1Universidade Federal da Bahia, Salvador, BA - Brasil.
Arquivos brasileiros de cardiologia
|June 4, 2025
概括
低密度脂蛋白 (LDL) 和甘油三可以预测流介导扩张 (FMD),这是内皮功能的一个关键标志物. 耐性高血压群体在糖化血红蛋白,和C反应蛋白水平上有差异.
科学领域:
- 心血管医学 心血管医学
- 内分泌学 在内分泌学.
- 临床化学 临床化学
背景情况:
- 高血压 (BP) 是心血管疾病,中风,病和死亡的主要危险因素.
- 支臂动脉流媒扩张 (FMD) 是一种标准的,非侵入性的内皮功能测量方法,也是心血管事件的预测指标.
研究的目的:
- 为了研究口和口病与各种血液参数之间的相关性.
- 为了比较患有变异性与未变化的口病患者之间的血液参数.
- 为了比较抗性高血压 (RHTN) 和非RHTN组之间的参数.
主要方法:
- 一个高血压诊所72名志愿者的前性横截面研究.
- 改变的口病 (n=38) 和不改变的口病 (n=34) 组之间的患者变量比较.
- 通过使用参数或非参数方法进行统计分析,比较RHTN (n=49) 和非RHTN (n=23) 组之间的患者变量.
主要成果:
- 在口病和LDL (p=0.042) 和甘油三 (p=0.037) 之间发现了显著的正相关性.
- 糖化血红蛋白在RHTN组中更高 (p=0.020),而在非RHTN组中更高 (p=0.029).
- 在RHTN组中,C-反应蛋白升高 (p=0.04),没有观察到其他显著差异.
结论:
- LDL和甘油三被认为是口病的预测因素.
- 抗性高血压和非抗性高血压组表现出不同水平的,C反应蛋白和糖化血红蛋白.
- 甘油三是唯一的参数,显示了改变和不改变的口疫群体之间的显著差异.
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