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Updated: Jun 14, 2025

Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation
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Published on: May 4, 2018

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无处方药和复合口水用于放射治疗诱导的异口症:一项随机对照试验

Isabella Silveira Savo1, Samanta Vicente de Oliveira1, Gabriela Banacu de Melo1

  • 1Universidade de São Paulo - School of Dentistry, Department of Stomatology, São Paulo, SP, Brazil.

Brazilian oral research
|June 4, 2025
PubMed
概括

两种唾液替代品可以暂时缓解头部和部放射治疗引起的口腔干燥 (xerostomia). 这项双盲试验发现,两种口水选择都显著减少了患者的异口症症状.

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5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
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