过度的白天嗜睡可能预测早期中风后认知障碍的老年人与非致残性缺血性中风
ZhenHui Lu1, XiaoMing Guo1, Can Xing1
1Department of Neurology, Affiliated Hospital 2 of Nantong University, Nantong 226001, China.
概括
在缺血性中风的急性阶段,过度的白天嗜睡 (EDS) 与老年患者的早期中风后认知障碍 (PSCI) 有关. 监测爱普沃思睡眠度量 (ESS) 评分可以帮助PSCI的早期诊断和干预.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 老年病的医生 老年病的医生
背景情况:
- 白天嗜睡是急性缺血性中风的常见问题,影响结果.
- 然而,它与中风后认知功能的关联仍然不清楚.
研究的目的:
- 调查过度白天嗜睡 (EDS) 与老年患者在非致残性缺血性中风后早期认知障碍之间的关系.
主要方法:
- 对患有急性非致残性缺血性中风 (NIHSS ≤3) 的老年患者 (>60岁) 的前性研究.
- 使用爱普沃思睡眠度量表 (ESS) 评估的过度白天睡眠 (EDS).
- 蒙特利尔认知评估 (MoCA) 在基线和随访时评估的认知功能;认知障碍定义为MoCA得分<26 (≥12年教育) 或<25 (<12年教育).
主要成果:
- 在243名患者中,有160名 (65.8%) 患有早期中风后认知障碍 (PSCI).
- 较高的急性阶段ESS得分与早期PSCI有显著的关联 (调整后OR为1.146,P=0.006).
- 确定ESS得分≥7作为早期PSCI (AUC0.593) 的预测因素.
结论:
- 在患有非致残性缺血性中风的老年患者中,早期的PSCI与急性阶段的EDS有关.
- 监测急性中风患者的ESS得分对于早期PSCI诊断和及时干预至关重要.
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