相关实验视频

Updated: Sep 19, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

9.2K

通过DNA编码图书馆选发现一种新的CD39抑制剂

Simin Wang1, Jiannan Zhao2, Takashi Nakai3

  • 1College of Chemistry, Zhengzhou University, Zhengzhou 450001, China; Pingyuan Laboratory, Zhengzhou 450001, China.

Bioorganic & medicinal chemistry letters
|June 4, 2025
PubMed
概括

研究人员使用DNA编码库技术发现了一种新的CD39小分子抑制剂,化合物338. 这种化合物显示出作为抗瘤治疗剂的希望,因为它具有强大的CD39抑制和良好的药物可用性.

关键词:
这是一种抗瘤药物.CD39 CD39 是一个一个DNA编码的图书馆.

更多相关视频

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype14:51

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype

Published on: June 17, 2022

3.3K
Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions06:01

Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions

Published on: January 7, 2019

7.3K

相关概念视频

Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
8.8K