无参考4D流动心血管磁共振与深度学习
Chiara Trenti1, Erik Ylipää2, Tino Ebbers3
1Department of Health, Medicine and Caring Sciences (HMV), Linköping University, Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping, Sweden.
概括
深度学习通过预测参考编码,显著减少四维 (4D) 流动心血管磁共振 (CMR) 的扫描时间. 这使得在临床实践中更快,更高分辨率的心血管评估成为可能.
科学领域:
- 心血管成像 - 心血管成像
- 医学物理 医学物理
- 人工智能在医学中的应用
背景情况:
- 四维 (4D) 流动心血管磁共振 (CMR) 对于评估心血管疾病至关重要,但受到长时间获取时间的限制.
- 传统的4D流CMR需要引用编码扫描,这有助于扩展扫描持续时间.
- 减少扫描时间对于改善4D流CMR的临床实用性和患者体验至关重要.
研究的目的:
- 开发和评估一种深度学习模型,用于预测4D流CMR中的参考编码.
- 为了实现无参考的4D流CMR采集,从而减少扫描时间,并可能提高图像分辨率.
- 与传统方法相比,评估基于深度学习的速度和流量量化的准确性.
主要方法:
- 使用对抗式学习 (U-NetADV) 和速度频率加权损失函数 (U-NetVEL) 训练了一个U-Net深度学习架构.
- 这些模型预测了来自126名患者的全心4D流数据集中的三种运动编码的参考编码.
- 定量评估包括主要心脏结构中的流量,速度和动动能.
主要成果:
- 深度学习预测的参考编码产生了与扫描仪获取的数据相比的3D速度数据.
- U-NetADV在整个心脏周期和受试者中表现一致,而U-NetVEL在心缩速度预测方面表现出色.
- 流量量和流速的量化误差一般很低,在动动能计算中的特殊例外.
结论:
- 基于深度学习的无参考4D流量CMR提供了速度和流量量的准确量化.
- 消除参考扫描将获得的数据减少25%,从而允许缩短扫描时间或更高分辨率.
- 这一进步为4D流CMR的常规临床应用带来了巨大的潜力.
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