肠道微生物组连接了营养和人类健康
Yolanda Sanz1, John F Cryan2,3, Mélanie Deschasaux-Tanguy4
1Microbiome Innovation in Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Valencia, Spain. yolsanz@iata.csic.es.
Nature reviews. Gastroenterology & hepatology
|June 4, 2025
概括
饮食和肠道微生物组显著影响健康. 了解它们的相互作用是公共卫生,精炼营养和个性化饮食建议以获得最佳福祉的关键.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 人类健康 人类健康 人类健康
背景情况:
- 肠道微生物组在调解饮食对健康的影响方面发挥着至关重要的作用.
- 低于最佳的饮食是导致疾病的主要原因.
- 了解饮食-微生物组-器官相互作用对于公共健康至关重要.
研究的目的:
- 审查饮食模式如何影响肠道微生物组的组成.
- 探索饮食与微生物相互作用对免疫,神经和心脏代谢系统的机制.
- 讨论个性化营养和饮食指南中的应用.
主要方法:
- 关于饮食,肠道微生物组和宿主生理学的当前研究的文献综述.
- 对微生物新陈代谢和宿主信号通路的发现进行综合.
- 分析证据,将微生物组调节与健康结果联系起来.
主要成果:
- 饮食模式显然塑造了肠道微生物组的特征.
- 饮食与微生物的相互作用会影响多个器官系统,影响免疫,神经和心脏代谢健康.
- 这种相互作用有助于解释饮食反应的个体变化.
结论:
- 将微生物组科学融入营养中,为优化健康提供了一条道路.
- 需要进一步的研究来弥合知识差距,以准确的饮食建议.
- 这一领域对于推进基于食品的指导方针和精准营养至关重要.
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