儿科 papillary 尿路细胞瘤:在诊断和治疗方面拥有18年的单一中心经验
1Department of Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 10045, China.
BMC urology
|June 4, 2025
概括
儿科膀泌尿瘤,通常呈现为粗血,通过超声波诊断. 虽然预后有利,但复发是可能的,在某些情况下,膀灌注化疗可能有助于预防它.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 儿科膀泌尿瘤是罕见的,但需要特定的诊断和管理方案.
- 了解尿路皮瘤 (UP) 和低恶性潜力的乳头尿路瘤 (PUNLMP) 之间的差异对于治疗规划至关重要.
研究的目的:
- 概述了儿科膀尿道瘤的诊断,治疗和随访方案.
- 为管理这些罕见疾病的儿科外科医生分享临床见解.
主要方法:
- 对17例儿科膀泌尿器瘤病例 (2006-2024) 的回顾性分析.
- 患者被分为尿路皮瘤 (UP) 和低恶性潜力的乳头尿路瘤 (PUNLMP) 组.
- 评估的主要结局是瘤复发.
主要成果:
- 所有17名患者都是男性,平均年龄为10.5岁.
- 大型出血是最常见的症状 (88.2%);超声波证实了诊断.
- 在82.3%的病例中进行了开放切除;确定了UP (11例) 和PUNLMP (6例).
- 在没有化疗的PUNLMP组中发生了一次复发;在膀灌注化疗后没有观察到复发.
结论:
- 儿童的大型出血需要对膀泌尿瘤进行评估,超声波扫描有助于诊断.
- 预后通常是有利的,但复发是可能的,需要超声监测.
- 针对PUNLMP的预防性膀灌注化疗可能会降低复发风险,需要进一步调查.
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