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在多发性硬化症中,炎症改变了髓质细胞和小质细胞的铁处理

Christian J Riedl1,2, Daniel Bormann1,2,3, Anja Steinmaurer2,4

  • 1Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, 1090, Austria.

Acta neuropathologica communications
|June 4, 2025
PubMed
概括

多发性硬化症 (MS) 涉及大脑的铁转移,铁在寡干细胞中丧失,并在髓状细胞中积累. 这项研究揭示了MS中铁失调的机制,突出了这些细胞对铁的改变处理.

关键词:
铁的损失 铁的损失铁边缘病变 铁边缘病变微质细胞中的微质细胞多发性硬化症是多发性硬化症.氧基质细胞 (Oligodendrocytes) 是一种类型的质细胞.

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