术后肠道蛋白质补充对重症儿童中平衡的影响
Irene Yuniar1, Kadek Apik Lestari1, Antonius Hocky Pudjiadi1
1Department of Child Health, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
高蛋白质的肠道营养显著改善了手术后重症儿童的平衡. 这种营养策略增强了无副作用的代谢,这对恢复至关重要.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 营养科学 营养科学
- 临床营养学 临床营养学
背景情况:
- 重症儿童在手术后面临营养不良的风险.
- 最佳营养是减少发病率和死亡率的关键.
- 关于肠道蛋白对平衡和I-FABP在这个人群中的影响的数据有限.
研究的目的:
- 为了确定增加肠道蛋白质摄入量是否会改善平衡 (NB).
- 评估较高的蛋白质摄入量是否会降低血清肠脂肪酸结合蛋白 (I-FABP) 水平.
- 为了评估术后重症儿童的影响.
主要方法:
- 双盲随机对照试验涉及76名儿童 (1-5岁).
- 标准蛋白质 (3.0 g/100 mL) 与高蛋白质 (4.35 g/100 mL) 肠道营养的比较.
- 在第1天和第3天评估NB; I-FABP测量在食前和后72小时.
主要成果:
- 高蛋白质组显示平均NB (283.4毫克/公斤/天) 与标准蛋白质组 (114.7毫克/公斤/天) 相比显著增加 (P<0.0001).
- 在这两组中都没有观察到I-FABP水平的显著降低.
- 高蛋白质补充导致改善平衡.
结论:
- 高蛋白质肠道补充剂有效地改善了术后重症儿童的平衡.
- 这种营养方法是安全的,似乎不会引起不良副作用.
- 进一步的研究可能会探索I-FABP的作用或替代标记物.
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