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Updated: Jun 16, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

Published on: October 23, 2018

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通过CASTOR1-GATOR2复合体进行mTORC1调节的结构基础

Rachel Jansen, Clement Maghe, Karla Tapia

    Research square
    |June 5, 2025
    PubMed
    概括

    氨酸水平调节mTORC1,这是一个关键的新陈代谢控制器. 这项研究揭示了氨酸传感器CASTOR1与GATOR2结合如何抑制GATOR1,在低氨酸条件下激活mTORC1.

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    A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation

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