ENTAiLS工具包:一个集成的工作流程,用于对多基和多基物质进行非向分析
Heather D Whitehead1, Timothy J Buckley2, Jon R Sobus2
1Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, USA. whitehead.heather@epa.gov.
Analytical and bioanalytical chemistry
|June 5, 2025
概括
公共卫生实验室现在可以更好地使用非向分析 (NTA) 监测和多基物质 (PFAS). 美国环保署 (EPA)
科学领域:
- 环境健康 环境健康
- 分析化学 分析化学
- 环境科学 环境科学
背景情况:
- 越来越多的人担心和多基基物质 (PFAS) 需要超越通常分析的有限数量的化合物进行更广泛的监测.
- 目前的有针对性的分析方法不足,测量不到100个PFAS化合物,而已知有数千个.
- 非定向分析 (NTA) 为了解PFAS发生提供了更全面的方法,但在公共卫生实验室中面临采用障碍.
研究的目的:
- 解决阻碍公共卫生实验室广泛采用非向分析 (NTA) 的障碍.
- 为环境样本,特别是饮用水中全面监测PFAS提供标准化和可访问的解决方案.
主要方法:
- 开发环境分析工具包以提供实验室研究信息 (ENTAiLS) 工具包.
- 创建一个公开可用的PFAS NTA最佳实践汇编.
- 实施一个开源数据处理工作流程,旨在为稳健的NTA应用程序设计.
主要成果:
- ENTAiLS工具包为PFAS NTA从业人员提供了全面的指导.
- 工具包中的综合工具有助于识别和描述更广泛的PFAS.
- 美国环保署的ORD和州实验室之间的技术合作推动了这个资源的开发.
结论:
- ENTAiLS工具包旨在克服公共卫生实验室采用NTA的现有障碍.
- 该工具包使实验室能够进行更彻底的PFAS发生研究.
- 现在可以更好地识别和描述饮用水资源中的PFAS.
更多相关视频
05:47In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox
Published on: August 28, 2019
14.1K
07:06Investigating Long-Distance Transport of Perfluoroalkyl Acids in Wheat via a Split-Root Exposure Technique
Published on: September 28, 2022
1.7K
相关概念视频
Tandem Mass Spectrometry
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
Sample Preparation for Analysis: Overview
Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
Sample Preparation for Analysis: Advanced Techniques
Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
