[对性传播感染的照顾点检测-目前的情况是什么?]
Viviane Bremer1, Heinrich Scheiblauer2, Maximilian Muenchhoff3
1Abt. für Infektionsepidemiologie, Robert Koch-Institut, Seestr. 10, 13353, Berlin, Deutschland. bremerv@rki.de.
概括
临床检测 (PoCTs) 快速诊断性传播感染 (STIs),有助于实现全球卫生目标. 虽然对艾滋病毒和梅毒有所改善,但对克拉米迪亚和淋病的PoCT质量仍然不足,需要进一步开发.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 诊断 诊断 诊断 诊断
背景情况:
- 照顾点检测 (PoCTs) 对于快速诊断性传播感染 (STIs) 至关重要,支持世卫组织到2030年减少艾滋病,肝炎和性传播感染的目标.
- 新的欧盟法规正在提高体外诊断的质量标准,包括STI PoCT,需要更严格的审查.
- 进展已经改善了针对艾滋病毒,梅毒和型肝炎的PoCT,并提供了世卫组织预先合格的选项.
研究的目的:
- 评估当前对性传播感染的临床检测的现状和挑战.
- 突出PoCTs在实现全球性疾病控制和传染病控制的全球卫生目标中的作用.
- 确定需要进一步发展的PoCT技术在STI的领域.
主要方法:
- 审查当前的点的护理测试技术的STIs.
- 对诊断试验质量的监管影响的分析.
- 对艾滋病毒,梅毒,克拉米迪亚和淋病等特定感染的PoCT性能评估.
主要成果:
- PoCT提供了对艾滋病毒,梅毒和型肝炎的改进测试,但局限性仍然存在,例如对艾滋病毒的确结果延迟,需要确认梅毒.
- 目前针对克拉米迪亚,淋病和菌等疾病的PoCT在很大程度上是不充分的.
- 核酸放大试验 (NAT) 对未来的STI PoCT开发有希望.
结论:
- PoCT对于可访问性传播感染的诊断和治疗至关重要,特别是对于边缘化群体.
- 质量保证和管理错误结果的心理影响是关键的挑战.
- 持续开发和整合PoCT对于改善诊断准入和减少感染传播至关重要.
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