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Updated: Sep 19, 2025

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MscL打开的不对称性被分子动力学模拟所揭示

Olga N Rogacheva1, Wojciech Kopec1,2

  • 1Computational Biomolecular Dynamics Group, Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany.

Journal of chemical information and modeling
|June 5, 2025
PubMed
概括

突变细菌机械敏感通道 MscL (L17A,V21A) 在压力下过渡到中间开放状态 (S1). 这项研究揭示了关键的分子事件和控制 MscL 门的能量景观,有助于阐明野生类型通道机制.

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