上肢关节疼痛作为评估类风湿性关节炎患者存在感的实际指标:一个横截面观察性研究
Ryota Naito1,2, Masashi Taniguchi1,2, Hideo Onizawa1,3
1Center for Rheumatic Diseases, Nagahama City Hospital, Shiga, Japan.
PloS one
|June 5, 2025
概括
患有上肢关节疼痛的类风湿性关节炎患者经历了显著的存在感,影响了工作表现. 减少肩膀和手指关节的疼痛是改善类风湿性关节炎中工作残疾的关键.
科学领域:
- 类风湿病学 类风湿病学
- 职业健康 职业健康 职业健康
- 流行病学 流行病学
背景情况:
- 类风湿性关节炎 (RA) 是一种慢性炎症性疾病,导致关节功能障碍和劳动生产率下降.
- 存在主义,或在工作中工作表现受损,是RA患者工作残疾的主要原因之一.
- 具体的关节参与,特别是上肢,对RA的存在感的影响需要进一步研究.
研究的目的:
- 在类风湿性关节炎患者中调查上肢关节卷入和表现症之间的关联.
- 为了确定上肢的特定关节,这些关节与呈现主义有显著的相关性.
- 探索关节疼痛和RA中的表现主义之间的纵向关系.
主要方法:
- 每年对RA门诊患者进行调查,使用工作生产力和活动障碍问卷 (WPAI).
- 多变量回归分析检查了截面和纵向的协会之间 presenteeism 和软关节计数 (TJC) 在 extremities.
- 这项研究包括201名RA患者,来自Nagahama Riumachi队列.
主要成果:
- 52%的RA患者报告了存在主义.
- 在三个或更多的上肢TJC和现场主义之间发现了显著的正相关性 (β = 17.9).
- 肩膀 (β = 9.55) 和手指 (β = 1.60) 的TJC与现场主义有显著的正相关性;下肢TJC没有.
结论:
- 上肢疼痛关节数量是类风湿性关节炎中存在症的重要预测因素.
- 针对上肢,特别是肩膀和手指的关节疼痛,可以减少工作残疾.
- 管理上肢关节干扰是改善RA患者工作能力的关键治疗目标.
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