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Updated: Sep 19, 2025

Directed Differentiation of Hemogenic Endothelial Cells from Human Pluripotent Stem Cells
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朱德编排了cis-调控元件的动态,以促进内皮细胞向血液构造细胞的过渡

Jiani Guo1, Mengyao Liu1, Feng Liu2

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China.

Proceedings of the National Academy of Sciences of the United States of America
|June 5, 2025
PubMed
概括

转录因子 (TFs) 和 cis调节元件 (CREs) 控制细胞命运. 这项研究揭示了AP-1和Hoxa9a TFs如何协作调节斑马鱼的内皮转化为血液生成转变 (EHT).

关键词:
AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1朱德·朱德 (Jund Jund) 是一个名字.这些是cis-regulatory元素.从内皮转变为血液形成的转变.造血干细胞和原始细胞.

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