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Updated: Sep 19, 2025

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晶氨酸稳定剂的差异性结合亲和和和动力学

Alan X Ji1, Andreas Betz, Uma Sinha

  • 1BridgeBio Pharma, Inc., San Francisco, CA.

Journal of cardiovascular pharmacology
|June 5, 2025
PubMed
概括

与tafamidis和diflunisal相比,阿科拉米迪斯表现出优异的跨氨酸 (TTR) 稳定性,为跨氨酸粉样心肌病 (ATTR-CM) 提供了增强的治疗潜力. 这种TTR稳定剂具有更高的结合亲和力和动力稳定性.

关键词:
在ATTR-CM中使用.转二烯是什么意思这就是阿科拉米迪斯 (acoramidis).结合性亲和力是一种结合性亲和力.

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