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Updated: Sep 19, 2025

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors

Published on: June 8, 2022

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将GPR101受体的模型和实验结构进行比较:人工智能能产生高度准确的模型

Stefano Costanzi1, Lea G Stahr1, Giampaolo Trivellin2

  • 1American University, Department of Chemistry, Washington, DC, USA.

Journal of molecular graphics & modelling
|June 5, 2025
PubMed
概括

人工智能 (AI) 模型,特别是AlphaFold2,在预测GPR101结构方面,与同类模型相比,显示出更高的准确性. 然而,对特定区域的同质模型仍然是有价值的,比如G蛋白结合的第六跨膜域.

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