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静脉内多克索鲁比辛诱导的膀收缩导致囊切除术:一个案例系列
Ahmed Aldolly1, Mohamad Yasin Lutfi2
1Faculty of Medicine, Hama University, Hama, Syria.
International journal of surgery case reports
|June 5, 2025
概括
用于膀癌的静脉注射多克索鲁比,很少会导致严重的膀收缩. 这种严重的副作用可能需要囊切除术,并需要监测膀容量.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- doxorubicin 是一种用于癌症治疗的抗生素.
- 与全身药物相比,静脉内注射多克索鲁比辛的系统性副作用较低.
- 膀表面过渡细胞癌是一种常见的诊断.
研究的目的:
- 报告严重的膀收缩作为静脉内多克索鲁比辛治疗的罕见并发症.
- 突出在这种情况下可能需要囊切除术和尿路转移.
主要方法:
- 介绍了两例膀癌的病例,这些病例是用静脉注射多克索鲁比辛治疗的.
- 患者在经尿道切除和静脉内治疗后出现严重的膀收缩.
- 随后需要进行彻底囊切除术和尿路转移.
主要成果:
- 经过静脉注射多克索鲁比辛治疗后,两名患者出现了严重的膀收缩.
- 这种罕见的并发症导致显著的发病率和囊切除术的需要.
结论:
- 严重的膀收缩是一种罕见但严重的不良事件,与静脉注射多克索鲁比辛相关.
- 这种并发症会严重影响患者的生活质量,可能需要进行激进的囊切除术.
- 在接受静脉内治疗的患者中,建议对膀容量的客观监测.
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